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Mesenchymaler (MSC) stem cells are found pluripotent cells several adult tissues, including bone marrow, synovial tissue and adipose tissue. How are derived from the mesoderm, should have been shown to differentiate into bone, cartilage, muscle tissue and fat. MSCS promised embryonic scientific sources when creating the greatest controversy. Thus, many researchers have focused on [1] adult stem cells or cells adult stem may be damaged isolated plant tissues. Thanks to its skills of multipotent of the mesenchymal stem cells (MSCS) are successful in animal models to regenerate bone and articular cartilage regenerate human models used were. Recent studies show that articular cartilage can be repaired capable of percutaneous introduction of the mesenchymal stem cells (MSCS). These marrow components can be divided into plasma, erythrocytes, platelets and nucleated cells. The Division of the adult stem cells in the marrow cells of bone nucleata. Most of these cells are CD34 + progenitors heme (designed to differentiate into blood components), while some are able to bone, cartilage or muscles several MSC a reality. It is still a very small number of MSC Vertriebs GmbH in the marrow cells differentiate into tissue of interest in joint preservation. It is one of the reasons might be, systems of centrifuge commercially available that serve marrow nucleated cells focus not as promising in animal studies of cartilage showed how approaches, where are the MSC Vertriebs GmbH, in the culture more. Bed side centrifugation is commonly used for this application. Once again, these techniques very dilute MSC population, generally producing a yield of 1 to 10. 000-1 000 000 of nucleated cells. Despite this low amount of MSC Vertriebs GmbH isolated bones showed promising marrow nucleated cells implanted in human peripheral joints degenerate for joint repair. SCMs can be isolated from the bone marrow of the bone is rather limited, research expanded regeneration of cartilage with cultured cells. This method can be extended up to number cells of 100-10 000 fold for several weeks. Once these MSCs ready to re-origin, are factors of growth of cells more from the damaged tissue to allow general distribution. At one point, enters a sign of cells is difference in final fabric (in this discussion, cartilage) (culture or after tissue transplantation). Until recently, it was the use of mesenchymal stem cells to regenerate cartilage grown mainly in research with animal models. At the same time, it has nevertheless published two reports on technology previous case is used to regenerate cartilage and knee joint meniscus successfully. This technique has already proven in a study with a larger group of patients, but the same team of researchers published study (n = 227) safety show less complications that would be normally associated with surgical procedures. Another team used a similar technique to extract the cell and ex vivo expansion, but the cells in a collagen gel were formed not yet implemented. Reported a case study where a lack of development of the total thickness of articular cartilage of a human knee repaired successfully. While the use of mesenchymal stem cells culture have shown promising results, a more recent study with histologically confirmed MSC were uncultivated in full force, the hyaline cartilage to grow back. Dr Saw Khay Yong and his team, the quality of the repair of the cartilage of the represented Knee arthroscopic microperforation (also microfractures) - operation, breast actives breast enhancement cream followed by postoperative peripheral blood stem cells autologous injections (PCV) in combination with hyaluronic acid (HA). The PCV is a blood product with MSC, obtained thanks to the mobilization of peripheral blood cells. In February 2011, the team published the results of a series of RS 5 patients. Five patients showed evidence of regeneration of hyaline cartilage on second look Arthroscopy and biopsy, including 2 patients with bipolar or embrace fully into force. The authors suggest that the pinholes of a blood clot of created the operation which added to the PCV may be recruited and improve chondrogenesis on the wound site content. You agree that the importance of this regeneration of cartilage of the Protocol which is successfully in patients with historically difficult to treat lesions bipolar grade IV of os or OS chondralen. Dr. Saw and his team perform a larger randomized trial and the beginning of a multi-center work. The Malaysian research team work gained international attention. .